Puzzle Category: Design

Puzzle
Description:In this category, players design proteins to create new materials, target problematic molecules in diseases, and enhance existing proteins - among other things. Protein design involves inserting and deleting the amino acids to/from the protein, and also changing which amino acids compose the protein.
Scoring:Your best 8 out of the last 10 Puzzles.



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1147b: 75 Residue Symmetric Dimer Design: Satisfied H-Bonds 10/18/15
1392: Large Monomer Design: Smaller Core 06/23/17
1909: Symmetric Tetramer Design: H-bond Networks 11/04/20
852: Trimer Interface Redesign: Round 2 03/06/14
2034: TGF Receptor Binder Design: Round 10 with AlphaFold Predictions 08/27/21
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(7/8/10)
OSX
(10.12 or later)
Linux
(64-bit)

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, Boehringer Ingelheim, RosettaCommons