puzzle picture
Beginner Puzzle: Anthrax Lethal Factor Protein
Status: Closed

Summary

Name: Beginner Puzzle: Anthrax Lethal Factor Protein
Status: Closed
Created: 05/04/2012
Points: 10
Expired: 06/04/2012 - 23:00
Difficulty: Beginner
Description: This puzzle is designed for veteran Foldit players to help new players, and since it was up recently this version of the puzzle is only worth 10 global points.
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1Go Science10,17610
2Anthropic Dreams10,0909
3L'Alliance Francophone10,0618
4Team Hungary10,0536
5Another Hour Another Point10,0505

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Comments

beta_helix's picture
User offline. Last seen 1 day 15 hours ago. Offline
Joined: 05/09/2008
Groups: None
Native guide scores: 9213.678

For those of you interested in knowing the score of the guide, it is at 9213.678. It has not been relaxed or fused at all, so you should be able to improve on that score if you reach the native state. (For example, fusing the native 3 times gives a score of 9415.568)
_______________________________________________________________

If you are new to Foldit, here are detailed instructions to get you started:
http://fold.it/portal/node/988864

HINT: If you are having trouble with this puzzle, try using the "Align Guide" tool:

By right clicking on a region of the protein (not the guide) it will pull up a menu with 6 tools. The bottom right one is "Align Guide". Clicking on it will align the native guide to the region of the protein you selected.
This will help you see what sections on your protein correspond to the guide!

Working with the guide is much more user friendly when you use the advanced viewing options.
In the game click on Menu->General Options and select "Show Advanced GUI" and click Done.
Click on View, turn on 'Show Outline,' set the background color to white, and view stubs on the sidechains, view the guide, and set color relative to guide. Turn all the other view options off."

For even more info: http://foldit.wikia.com/wiki/Tlaloc%27s_Strategy#Technique_for_Matching_a_Guide

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons