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549 (<150): Beginner Immunotherapy Design Puzzle 2
Status: Closed

Summary

Name: 549 (<150): Beginner Immunotherapy Design Puzzle 2
Status: Closed
Created: 04/26/2012
Points: 50
Expired: 05/04/2012 - 17:00
Difficulty: Beginner
Description: We are giving you a 8 residue long helix that you are able to mutate & dock onto the native binding region which is indicated by the side chains that are allowed to shake. Try to look for favorable hydrophobic interactions and strong hydrogen bonds, while maintaining the helix! If you are new to Foldit, make sure you have completed Intro Puzzle 5-2, and 7-1 through 7-4 before trying this puzzle.
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beta_helix's picture
User offline. Last seen 3 days 30 min ago. Offline
Joined: 05/09/2008
Groups: None
START HERE:

If you are new to Foldit, here are detailed instructions to get you started:
http://fold.it/portal/node/988864

You can learn more about these Immunotherapy Puzzles in the blog:
http://fold.it/portal/node/992285

Get Started: Download
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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons