puzzle picture
487: CASP ROLL Puzzle 1
Status: Closed

Groups

RankGroupScorePoints
1Contenders12,214100
2Go Science12,05084
3Void Crushers11,98470
4Anthropic Dreams11,94358
5Androids11,90847
6L'Alliance Francophone11,90639
7foldeRNA11,60632
8Russian team11,56126
9Trailer Trash11,52621
10BOINC@Poland11,50516
11Foldit UK11,38513
12Team Tornado11,36510
13chillerdown11,2648
14BOINC.Italy11,0906
15SETI.Germany11,0855
16Natural Abilities10,9154
17Slovak National Team10,8333
18Worldthink.pl10,8012
19FoldIt@Netherlands10,7962
20Freedom Folders10,7711
21Team Germany10,6841
22Mojo Risin'10,5081
23Mmm Helix Fries.10,1321
24Valencia10,1221
25Crunching Family10,0171


Need this puzzle? Log in to download.  

Comments

beta_helix's picture
User offline. Last seen 1 day 13 hours ago. Offline
Joined: 05/09/2008
Groups: None
Please try to use these secondary structure predictions:

Here is the sequence logo predicted by the SAM server.

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Valine at residue 3 is highly predicted to be part of a sheet. However, the Valine at residue 116 is predicted to be anything.

Joined: 06/25/2011
Groups: Androids
Regarding the W-Y-I sequence at 26-28...

It seems like the placement and identity of the other segments force that sequence to be a loop, rather than a (as predicted by the server to be slightly more likely) sheet.

B_2's picture
User offline. Last seen 7 years 4 weeks ago. Offline
Joined: 11/29/2008
Groups: None
Is this a previously unsolved

Is this a previously unsolved protein, or is this just enhancing a known or previously predicted structure?

I can't tell from the CASP site, since 90% of what's on there is gibberish to a layman.

beta_helix's picture
User offline. Last seen 1 day 13 hours ago. Offline
Joined: 05/09/2008
Groups: None
CASP ROLL just started last week

so these are all blind targets where the natives have not been released yet.
Here is the target list so you can see when the expiration deadlines are: http://predictioncenter.org/casprol/targetlist.cgi

User login
Download links:
  Windows    OSX    Linux  
Windows
(7/8/10)
OSX
(10.12 or later)
Linux
(64-bit)

Are you new to Foldit? Click here.

Are you a student? Click here.

Are you an educator? Click here.
Social Media


Search
Only search fold.it
Other Games: Mozak
Recommend Foldit
Topics
Top New Users
Sitemap

Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, Boehringer Ingelheim, RosettaCommons