puzzle picture
478 (<150): New Player Puzzle: Mycobacterium Tuberculosis Protein
Status: Closed

Evolvers

RankPlayerGroupScorePoints
1wiz91 70 1803  9,120100


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beta_helix's picture
User offline. Last seen 2 hours 1 min ago. Offline
Joined: 05/09/2008
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START HERE:

if you are new to Foldit, here are detailed instructions to get you started:
http://fold.it/portal/node/988864

HINT: If you are having trouble with this puzzle, try using the "Align Guide" tool:

By right clicking on a region of the protein (not the guide) it will pull up a menu with 6 tools. The bottom right one is "Align Guide". Clicking on it will align the native guide to the region of the protein you selected.
This will help you see what sections on your protein correspond to the guide!

Working with the guide is much more user friendly when you use the advanced viewing options.
In the game click on Menu->General Options and select "Show Advanced GUI" and click Done.
Click on View, turn on 'Show Outline,' set the background color to white, and view stubs on the sidechains, view the guide, and set color relative to guide. Turn all the other view options off."

For even more info: http://foldit.wikia.com/wiki/Tlaloc%27s_Strategy#Technique_for_Matching_a_Guide

Loosend's picture
User offline. Last seen 3 years 20 weeks ago. Offline
Joined: 11/08/2011
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Beginners Mycobacterium- sooooo stuck!

I keep making this protein WORSE! I'll try the Align thing again and see if I do better, but it's getting rather unrewarding continually stuffing it up!
Anyone else being a klutz on this one?

Paris07's picture
User offline. Last seen 10 years 1 week ago. Offline
Joined: 11/19/2011
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joining

how can I join

beta_helix's picture
User offline. Last seen 2 hours 1 min ago. Offline
Joined: 05/09/2008
Groups: None
START HERE:

if you are new to Foldit, here are detailed instructions to get you started:
http://fold.it/portal/node/988864

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, Boehringer Ingelheim, RosettaCommons