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458c: Electron Density Puzzle 3 Reposted
Status: Closed


Name: 458c: Electron Density Puzzle 3 Reposted
Status: Closed
Created: 10/19/2011
Points: 100
Expired: 10/22/2011 - 23:00
Difficulty: Intermediate
Description: This is the re-release of puzzle 458 that was taken down. We've resolved the issues with the puzzle, and it is now available for play again. You may load in your solutions from the original puzzle, or start fresh on it if you hadn't had a chance to play it before. Be sure to play the Electron Density Intro puzzle if you haven't already.
Categories: Electron Density, Overall, Prediction

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Joined: 06/17/2010
Updated client.

This puzzle need an updated client.
If you want to play you need close client, open it and allow to download latest update.

infjamc's picture
User offline. Last seen 6 hours 49 min ago. Offline
Joined: 02/20/2009
Groups: Contenders

Addendum to Rav3n_pl's notes:

Even if your client is the latest version, it might be a good idea to close the program and re-load it before trying to load this puzzle. (When I loaded this puzzle for the first time after loading another puzzle first, Foldit crashed. But the puzzle loaded successfully the second time upon restarting the program.)

Joined: 06/17/2010
Old saves.

You can load old save, but you can not share it to group.
Only new saves can be shared.
When you will try share old save client will crash.

spmm's picture
User offline. Last seen 7 weeks 4 days ago. Offline
Joined: 08/05/2010
Groups: Void Crushers
score change when aligning

the protein is flipping and turning and changing score when I hit the align protein to density button. I have not flipped or spun the protein as yet. Is this expected behaviour?

jflat06's picture
User offline. Last seen 12 hours 52 min ago. Offline
Joined: 09/29/2010
Groups: Window Group

If you are using the normal align (Not the refined align), then yes - the normal align tries to do some guesswork to figure out roughly where the major pieces go before doing a refined align to finish up. However, on some puzzles, it doesn't work so well. This one is a problem because the 4 parallel helices can "roughly" fit the density in many different ways, and it's having trouble finding the right one. So this is why it's flipping the protein; it just thinks it's better the other way around (even if that's wrong).

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, Boehringer Ingelheim, RosettaCommons