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469: De-novo Freestyle 14
Status: Closed

Summary

Name: 469: De-novo Freestyle 14
Status: Closed
Created: 10/17/2011
Points: 100
Expired: 10/25/2011 - 10:00
Difficulty: Advanced
Description: We are giving you this currently unsolved protein as an extended chain. Use all your beta-sheet forming skills to fold it up as best as you can. The secondary structure predictions are posted in the puzzle comments, but we have included them in the starting structure as well.
Categories: Overall, Prediction

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1Anthropic Dreams10,478100
2Androids10,46183
3Contenders10,45569
4Void Crushers10,43857
5foldeRNA10,30546

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Comments

beta_helix's picture
User offline. Last seen 19 hours 47 min ago. Offline
Joined: 05/09/2008
Groups: None
Please try to use these secondary structure predictions:

Here is the sequence logo predicted by the SAM server.

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the amino acid Valine at residue 12 is highly predicted to be part of a sheet. However, the Valine at residue 41 has an equal probability of being anything.

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons