460: Quest to the SOLVED Monkey Virus Protein

Summary

Name:

Status:

Closed

Created:

09/23/2011

Points:

100

Expired:

10/03/2011 - 23:00

Difficulty:

Intermediate

Description:

The crystal structure of monomeric M-PMV retroviral protease, which causes AIDS in rhesus monkeys, has finally been released. You may have read about this protein in the news recently... so we thought we should post it again as a Quest to the Native. Once again we are giving you the 10 NMR models to work on, they are also in the Alignment Tool. After threading, make sure to press G to Align the Guide. We're sure you can get even closer to the native this time, and in less than 10 days!

Categories:

Overall, Prediction

Rank

Group

Score

Points

Void Crushers

10,577

100

10,473

10,469

10,467

10,465

Rank

Player

Group

Score

Points

Simek 70 342

Void Crushers

10,575

100

Mike Cassidy 70 48

Void Crushers

10,537

100

10,535

10,473

10,469

Rank

Player

Group

Score

Points

Madde 70 1475

Void Crushers

10,577

100

10,444

10,415

10,406

10,400

Fri, 09/23/2011 - 04:46

beta_helix 70 991

Offline

Joined: 05/09/2008

Groups: None

This was the famous Unsolved Monkey Virus Protein

This is the Quest to the Native version of Puzzle 390:
http://fold.it/portal/node/989012

Now that the protein has been solved (thanks to all of you), the PDB has posted the solution:
http://pdb.rcsb.org/pdb/explore.do?structureId=3SQF

For hints on how to use Partial Threading with the Alignment Tool, check out: http://fold.it/portal/node/989012#comment-9780

And if you weren't playing Foldit last December and want to see if you would have been able to get close to the native, you can always turn off the guide by press Shift-S.