puzzle picture
452: De-novo Freestyle 13
Status: Closed


Name: 452: De-novo Freestyle 13
Status: Closed
Created: 08/29/2011
Points: 100
Expired: 09/07/2011 - 11:00
Difficulty: Advanced
Description: We are giving you this currently unsolved protein as an extended chain. Use all your beta-sheet forming skills to fold it up as best as you can. The secondary structure predictions are posted in the puzzle comments, but we have included them in the starting structure as well.
Categories: Overall, Prediction

Top Groups

1Void Crushers11,022100
4L'Alliance Francophone10,66334
5Anthropic Dreams10,65323

Top Evolvers

Top Soloists

1steveB 60 2065 Void Crushers10,992100
2aap 60 2065  10,91697
3mimi 60 2065 Contenders10,85593
4wudoo 60 2065 foldeRNA10,81989
5deus911 60 95 foldeRNA10,77486

Need this puzzle? Log in to download.  


beta_helix's picture
User offline. Last seen 33 min 41 sec ago. Offline
Joined: 05/09/2008
Groups: None
Please try to use these secondary structure predictions:

Here is the sequence logo predicted by the SAM server.

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the amino acid Leucine at residue 87 is highly predicted to be part of a sheet. However, the Serine at residue 81 has an equal probability of being anything.


Because this is a long protein, we are giving you 1 extra day to work on it.

User login
Download links:
  Windows    OSX    Linux  
(10.12 or later)

Are you new to Foldit? Click here.

Are you a student? Click here.

Are you an educator? Click here.
Social Media

Only search fold.it
Other Games: Mozak
Recommend Foldit
Top New Users

Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, Boehringer Ingelheim, RosettaCommons