puzzle picture
444: De-novo Freestyle 11
Status: Closed


Name: 444: De-novo Freestyle 11
Status: Closed
Created: 08/03/2011
Points: 100
Expired: 08/10/2011 - 16:00
Difficulty: Advanced
Description: We are giving you this currently unsolved protein as an extended chain. Use all your skills to fold it up as best as you can. The secondary structure predictions are posted in the puzzle comments, but we have included them in the starting structure as well.
Categories: Overall, Prediction

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beta_helix's picture
User offline. Last seen 6 hours 31 min ago. Offline
Joined: 05/09/2008
Groups: None
Please try to use these secondary structure predictions:

Here is the sequence logo predicted by the SAM server.

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the amino acid Leucine at residue 79 is highly predicted to be part of a helix. However, the Isoleucine at residue 65 has an equal probability of being anything.

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
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