puzzle picture
Beginner Puzzle (<150): Cold Shock Protein
Status: Closed

Summary

Name: Beginner Puzzle (<150): Cold Shock Protein
Status: Closed
Created: 07/23/2011
Points: 100
Expired: 08/23/2011 - 23:00
Difficulty: Beginner
Description: This is a Beginner puzzle for new players that have recently completed the Intro Puzzles. The starting model is all wrong, can you use the Foldit tools you just learned to improve the model and match the guide? For players with fewer than 150 global points.
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Comments

beta_helix's picture
User offline. Last seen 44 min 58 sec ago. Offline
Joined: 05/09/2008
Groups: None
START HERE:

if you are new to Foldit, here are detailed instructions to get you started:
http://fold.it/portal/node/988864

HINT: If you are having trouble with this puzzle, try using the "Align Guide" tool:

By right clicking on a region of the protein (not the guide) it will pull up a menu with 6 tools. The bottom right one is "Align Guide". Clicking on it will align the native guide to the region of the protein you selected.
This will help you see what sections on your protein correspond to the guide!

Working with the guide is much more user friendly when you use the advanced viewing options.
In the game click on Menu->General Options and select "Show Advanced GUI" and click Done.
Click on View, turn on 'Show Outline,' set the background color to white, and view stubs on the sidechains, view the guide, and set color relative to guide. Turn all the other view options off."

For even more info: http://foldit.wikia.com/wiki/Tlaloc%27s_Strategy#Technique_for_Matching_a_Guide

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons