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437: Multi-Start Server Models
Status: Closed

Summary

Name: 437: Multi-Start Server Models
Status: Closed
Created: 07/05/2011
Points: 100
Expired: 07/12/2011 - 20:00
Difficulty: Intermediate
Description: We are giving you 5 server models as starts for this puzzle. Each time you reset the puzzle one of these 5 Zhang server predictions will randomly be chosen. They are also in the Alignment Tool so you can use partial threading and well as an extended chain. We would like to see how well you can refine these models that were not generated using Rosetta.
Categories: Overall, Prediction

Top Groups

RankGroupScorePoints
1foldeRNA10,268100
2Void Crushers10,24178
3Contenders10,23460
4Anthropic Dreams10,23146
5Go Science10,23034

Top Evolvers

RankPlayerGroupScorePoints
1krulon 90 1808 foldeRNA10,268100
2cbwest 90 66 foldeRNA10,26797
3itskimo 90 1808 foldeRNA10,26694
4wudoo 90 1808 foldeRNA10,26491
5bertro 90 101 foldeRNA10,26288

Top Soloists



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Comments

beta_helix's picture
User offline. Last seen 1 day 11 hours ago. Offline
Joined: 05/09/2008
Groups: None
additional information on partial threading here ...

http://fold.it/portal/node/989193#comment-9965

And if you are new to Foldit, here are detailed instructions to get you started:
http://fold.it/portal/node/988864

gramps's picture
User offline. Last seen 4 years 42 weeks ago. Offline
Joined: 12/16/2010
437 model reset scores and starting structures

*** alignment tool users please see below for ***
*** important warning on Reset Structures function ***

(this comment presents supplementary information relevant to puzzle 437 folders who are into structures, threading and multiple models; if you're not doing any of that you probably can safely ignore the rest of this text)

The initial score displayed when you first started puzzle 437 or the first score displayed when you last reset the puzzle is one of the following five, depending on which alignment model you were randomly assigned.

Model.. --- Restart Score
----------------------
Zhang1 ----- 3598.554
Zhang2 ----- -543.442
Zhang3 ----- 1725.146
Zhang4 ----- -28236.221
Zhang5 ----- 1959.184

The five Zhang models each have distinct structures. If you haven't partial-threaded or manually adjusted your model's structure (changed loop/helix/sheet at any segment) then if you run the recipe "Report on Structures v0.03" ( https://fold.it/portal/recipe/16511 ) and compare its output with the following you'll be able to see which model was used for either your last complete threading, your last reset, or when you started the puzzle.

Starting Structures:

Zhang1 reset score: 3598.554

Loop Alfa(1,9); Sheet Bravo(10,10); Loop Charlie(11,15); Sheet Delta(16,21);
Loop Echo(22,23); Sheet Foxtrot(24,29); Loop Golf(30,36); Sheet Hotel(37,42);
Loop India(43,47); Sheet Juliet(48,48); Loop Kilo(49,58); Sheet Lima(59,63);
Loop Mike(64,70); Sheet November(71,77); Loop Oscar(78,81); Sheet Papa(82,88);
Loop Quebec(89,90)

Zhang2 reset score: -543.442

Loop Alfa(1,17); Sheet Bravo(18,21); Loop Charlie(22,23); Sheet Delta(24,28);
Loop Echo(29,36); Sheet Foxtrot(37,42); Loop Golf(43,47); Sheet Hotel(48,50);
Loop India(51,58); Sheet Juliet(59,63); Loop Kilo(64,70); Sheet Lima(71,77);
Loop Mike(78,81); Sheet November(82,88); Loop Oscar(89,90)

Zhang3 reset score: 1725.146

Loop Alfa(1,4); Helix Bravo(5,8); Loop Charlie(9,16); Sheet Delta(17,18);
Loop Echo(19,20); Sheet Foxtrot(21,21); Loop Golf(22,22); Sheet Hotel(23,23);
Loop India(24,35); Sheet Juliet(36,42); Loop Kilo(43,47); Sheet Lima(48,54);
Loop Mike(55,70); Sheet November(71,78); Loop Oscar(79,80); Sheet Papa(81,88);
Loop Quebec(89,90)

Zhang4 reset score: -28236.221

Loop Alfa(1,9); Sheet Bravo(10,10); Loop Charlie(11,18); Sheet Delta(19,20);
Loop Echo(21,23); Sheet Foxtrot(24,26); Loop Golf(27,36); Sheet Hotel(37,42);
Loop India(43,46); Sheet Juliet(47,49); Loop Kilo(50,57); Sheet Lima(58,58);
Loop Mike(59,61); Sheet November(62,63); Loop Oscar(64,70); Sheet Papa(71,78);
Loop Quebec(79,80); Sheet Romeo(81,88); Loop Sierra(89,90)

Zhang5 reset score: 1959.184

Loop Alfa(1,9); Sheet Bravo(10,10); Loop Charlie(11,15); Sheet Delta(16,21);
Loop Echo(22,23); Sheet Foxtrot(24,29); Loop Golf(30,35); Sheet Hotel(36,42);
Loop India(43,47); Sheet Juliet(48,53); Loop Kilo(54,58); Sheet Lima(59,63);
Loop Mike(64,70); Sheet November(71,78); Loop Oscar(79,80); Sheet Papa(81,88);
Loop Quebec(89,90)

***IMPORTANT***
Running a complete threading using the alignment tool does ***not*** reset the functionality of Actions --> Reset Structures.

Example:
Suppose when you started puzzle 437 the game randomly selected model Zhang2 (your start score was -543.442), but you later used the alignment tool to completely rethread to model Zhang4. Now you're folding with the Zhang4 structure, but if you later chose to Reset Structures, the reset would be to the original Zhang2 structure, which is quite different.

It's easy (if a bit tedious) to fix this problem should it occur, it's just useful to know that the Reset Structures button may become "hot" after a complete rethread. HINT: if you want to reset the game (perhaps in a new track) to a fresh start with a particular one of the models in mind, consider doing repeated resets until you get the reset score of the desired model. Then you can thread on that model, and Reset Structures will work as you would expect.

Further Technical Twist: the hot keys Save Structures (Ctrl+Shift+9) and Load Structures (Ctrl+9) can ***not*** be used to export structures between tracks. This just makes the task of restoring one of the five starting structures in the above scenario a bit more delicate.

gramps's picture
User offline. Last seen 4 years 42 weeks ago. Offline
Joined: 12/16/2010
Starting Structures (re-post for readability)

Zhang1 reset score: 3598.554

Loop Alfa(1,9); Sheet Bravo(10,10); Loop Charlie(11,15);
Sheet Delta(16,21); Loop Echo(22,23); Sheet Foxtrot(24,29);
Loop Golf(30,36); Sheet Hotel(37,42); Loop India(43,47);
Sheet Juliet(48,48); Loop Kilo(49,58); Sheet Lima(59,63);
Loop Mike(64,70); Sheet November(71,77); Loop Oscar(78,81);
Sheet Papa(82,88); Loop Quebec(89,90)

Zhang2 reset score: -543.442

Loop Alfa(1,17); Sheet Bravo(18,21); Loop Charlie(22,23);
Sheet Delta(24,28); Loop Echo(29,36); Sheet Foxtrot(37,42);
Loop Golf(43,47); Sheet Hotel(48,50); Loop India(51,58);
Sheet Juliet(59,63); Loop Kilo(64,70); Sheet Lima(71,77);
Loop Mike(78,81); Sheet November(82,88); Loop Oscar(89,90)

Zhang3 reset score: 1725.146

Loop Alfa(1,4); Helix Bravo(5,8); Loop Charlie(9,16);
Sheet Delta(17,18); Loop Echo(19,20); Sheet Foxtrot(21,21);
Loop Golf(22,22); Sheet Hotel(23,23); Loop India(24,35);
Sheet Juliet(36,42); Loop Kilo(43,47); Sheet Lima(48,54);
Loop Mike(55,70); Sheet November(71,78); Loop Oscar(79,80);
Sheet Papa(81,88); Loop Quebec(89,90)

Zhang4 reset score: -28236.221

Loop Alfa(1,9); Sheet Bravo(10,10); Loop Charlie(11,18);
Sheet Delta(19,20); Loop Echo(21,23); Sheet Foxtrot(24,26);
Loop Golf(27,36); Sheet Hotel(37,42); Loop India(43,46);
Sheet Juliet(47,49); Loop Kilo(50,57); Sheet Lima(58,58);
Loop Mike(59,61); Sheet November(62,63); Loop Oscar(64,70);
Sheet Papa(71,78); Loop Quebec(79,80); Sheet Romeo(81,88);
Loop Sierra(89,90)

Zhang5 reset score: 1959.184

Loop Alfa(1,9); Sheet Bravo(10,10); Loop Charlie(11,15);
Sheet Delta(16,21); Loop Echo(22,23); Sheet Foxtrot(24,29);
Loop Golf(30,35); Sheet Hotel(36,42); Loop India(43,47);
Sheet Juliet(48,53); Loop Kilo(54,58); Sheet Lima(59,63);
Loop Mike(64,70); Sheet November(71,78); Loop Oscar(79,80);
Sheet Papa(81,88); Loop Quebec(89,90)

beta_helix's picture
User offline. Last seen 1 day 11 hours ago. Offline
Joined: 05/09/2008
Groups: None
gramps,

Would all this be a bit easier if we got around to fixing this feedback?
http://fold.it/portal/node/988843

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
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