Perhaps a future without energy terms
|Opened on:||Wednesday, June 22, 2011 - 23:16|
|Last modified:||Saturday, June 25, 2011 - 07:30|
it occurred to me while talking to anthunk regarding the role quantum entanglement plays in human "imagination" that even a mind with a powerful imagination still must be trained to follow the folding rules proteins undergo.. or atleast I thought this was true.
It may be possible to design a software which is allowed to formulate it's own rules of physics, unbounded by Rosetta energy terms, to find it's own way toward the Native fold. The software would be given no a priori knowledge of physics, but only a direct access to the NMR data (as a guide) as well as an en vivo folding environment to commence comparative folding. As the machine learns and becomes proficient, you can then ask it for it's rules. The rules it gives you will be the Rosetta terms.