puzzle picture
432: De-novo Freestyle 8
Status: Closed


Name: 432: De-novo Freestyle 8
Status: Closed
Created: 06/18/2011
Points: 100
Expired: 06/25/2011 - 19:00
Difficulty: Advanced
Description: We are giving you this currently unsolved protein as an extended chain. Use all your skills to fold it up as best as you can. The secondary structure predictions are posted in the puzzle comments, but we have included them in the starting structure as well.
Categories: Overall, Prediction

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1Anthropic Dreams10,048100
4Void Crushers9,87148
5Go Science9,80837

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1wudoo 60 2065 foldeRNA10,00298
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5martinzblavy 60 2065  9,86688

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beta_helix's picture
User offline. Last seen 17 min 43 sec ago. Offline
Joined: 05/09/2008
Groups: None
Please try to use these secondary structure predictions:

As requested in the feedback, http://fold.it/portal/node/989298 these secondary structure predictions have been pre-loaded into this freestyle puzzle.

Here is the sequence logo predicted by the SAM server.

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the amino acid Leucine at residue 83 is highly predicted to be part of a sheet. However, the Phenylalanine at residue 29 is equally predicted to be in a sheet or loop (so it's probably not in a helix!).

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
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