Problem with T-cell Lymphoma Invasion Protein physics?
Case number: | 699969-989567 |
Topic: | General |
Opened by: | BootsMcGraw |
Status: | Closed |
Type: | Bug |
Opened on: | Monday, April 18, 2011 - 03:52 |
Last modified: | Tuesday, August 23, 2011 - 17:25 |
I've stumbled upon an odd development while working the T-cell Lymphoma Invasion Protein.
The loop between 9-Isoleucine and 15-Phenylalanine is acting strangely. At the end of a rebuild script, the highest scoring structure had this loop literally bent back upon itself (see figure1.png). When I tried to rebuild it manually, it stretched out to freakish proportions, and the score dropped to negative infinity. (Well, close enough.) I was too flabbergasted to get a screenshot.
When I did manage to get the loop back into a more reasonable shape, I shook the sidechains. 11-Lysine decided to then bury itself INSIDE the backbone (see figure2.png and figure3.png for before and after photos).
I call "BUG!" This protein ain't behavin'.
Attachment | Size |
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figure1.png | 24.05 KB |
figure2.png | 31.06 KB |
figure3.png | 31.15 KB |
It looks to me like ci=0 rebuild resoult, not a bug...
Actually, it's a feature rather than a bug :-)
According to the developers' official reply ( see http://fold.it/portal/node/989418 ), the abnormal backbone in the 9-15 loop was intentional because several residues were missing.
Status: Open » Closed |
Thanks for pointing to that, infjamc... Closing feedback.
Status: Closed » Closed |
Marking as resolved.
Changing "Type" to "Bug".