puzzle picture
410: De-novo Freestyle 5
Status: Closed

Summary

Name: 410: De-novo Freestyle 5
Status: Closed
Created: 04/04/2011
Points: 100
Expired: 04/12/2011 - 23:00
Difficulty: Advanced
Description: We are giving it to you this currently unsolved protein as an extended chain. Use all your skills to fold it up as best as you can. The secondary structure predictions are posted in the puzzle comments, but we have included them in the starting structure as well. Since this protein chain is quite long, we are giving you 2 extra days to work on it.
Categories: Overall, Prediction

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Comments

beta_helix's picture
User offline. Last seen 3 hours 6 min ago. Offline
Joined: 05/09/2008
Groups: None
Please try to use these secondary structure predictions:

As requested in the feedback, http://fold.it/portal/node/989298 these secondary structure predictions have been pre-loaded into this freestyle puzzle.

Here is the sequence logo predicted by the SAM server.

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the amino acid Isoleucine at residue 23 is highly predicted to be part of a helix. However, the Threonine at residue 102 is predicted to have an equal probability of being anything.

Joined: 04/07/2011
Groups: None
Convenient

Kinda hard to download I wish it were already loaded onto the site but it's a fun and educational game. I'd rate it four point five stars out of five stars.

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons