puzzle picture
406: Freestyle Nitric Oxide Puzzle
Status: Closed


Name: 406: Freestyle Nitric Oxide Puzzle
Status: Closed
Created: 03/22/2011
Points: 100
Expired: 03/28/2011 - 23:00
Difficulty: Advanced
Description: ***SEQUENCE LOGO NOW POSTED IN PUZZLE COMMENTS*** There will be more puzzles about this currently unsolved protein, but we wanted to start you off with it as an extended chain. Use all your skills to fold it up as best as you can. We will post a blog with details about this protein soon!
Categories: Overall, Prediction

Top Groups

1Anthropic Dreams12,155100
4Pauling's Pitbulls11,99841
5Void Crushers11,77530

Top Evolvers

Top Soloists

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Joined: 05/09/2008
Groups: None
secondary structure predictions
The SAM T08 server seems to be down, so we used some basic secondary structure predictions (which are the ones shown in the puzzle) We'll post a sequence logo when the SAM server comes back up!
Joined: 05/09/2008
Groups: None
sequence logo

Here is the sequence logo predicted by the SAM server.

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the amino acid Isoleucine at residue 25 is highly predicted to be part of a helix. However, the Leucine at residue 133 is predicted to be part of a beta sheet.

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons