puzzle picture
404: De-novo Freestyle 4
Status: Closed

Summary

Name: 404: De-novo Freestyle 4
Status: Closed
Created: 03/09/2011
Points: 100
Expired: 03/16/2011 - 23:00
Difficulty: Advanced
Description: This currently unsolved protein does not have any templates that we can use, so we are giving it to you as an extended chain. Use all your skills to fold it up as best as you can. The secondary structure predictions are posted in the puzzle comments, but we have included them in the starting structure as well.
Categories: Overall, Prediction

Top Groups

RankGroupScorePoints
1Contenders10,474100
2Anthropic Dreams10,46976
3foldeRNA10,30256
4Go Science10,28541
5Void Crushers10,26730

Top Evolvers

Top Soloists

RankPlayerGroupScorePoints
1Mark- 80 1347 Contenders10,472100
2keypad5 80 1347 Anthropic Dreams10,44198
3grabhorn 80 1347 Contenders10,34195
4aap 80 1347  10,33893
5deus911 80 1347 foldeRNA10,30090


Need this puzzle? Log in to download.  

Comments

beta_helix's picture
User offline. Last seen 1 day 16 hours ago. Offline
Joined: 05/09/2008
Groups: None
Please try to use these secondary structure predictions:

As requested in the feedback, http://fold.it/portal/node/989298, these secondary structure predictions have been pre-loaded into this freestyle puzzle.

Here is the sequence logo predicted by the SAM server.

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the amino acid Isoleucine at residue 29 is highly predicted to be part of a helix. However, the Leucine at residue 97 is predicted to have an equal probability of being anything.

Joined: 03/09/2011
Groups: None
Purpose?

What would this protein do, ideally, if a solution were found?

beta_helix's picture
User offline. Last seen 1 day 16 hours ago. Offline
Joined: 05/09/2008
Groups: None
I believe it is an RNA-binding protein
Get Started: Download
  Windows    OSX    Linux  
Windows
(7/8/10)
OSX
(10.7 or later)
Linux
(64-bit)

Are you new to Foldit? Click here.

Are you a student? Click here.

Are you an educator? Click here.
Search
Only search fold.it
Recommend Foldit
User login
Soloists
Evolvers
Groups
Topics
Top New Users
Sitemap

Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons