Stretchy AAs

Case number:845833-989331
Topic:Game: Display
Opened by:scottyler89
Status:Closed
Type:Bug
Opened on:Monday, February 28, 2011 - 00:58
Last modified:Sunday, June 5, 2011 - 17:33

This is the most random bug, but I added 2 AAs to one end on 402, clicked wiggle, and two of the AAs got really stretched out and enlarged, and won't go back to normal size. I hit undo until it was back to normal, tried it again, and the same thing happened.

I saved the protein before and after wiggle states if you want to look at them, and attached an image of it.

Very odd bug...

AttachmentSize
stretchy AA.png629.1 KB
(Mon, 02/28/2011 - 00:58  |  5 comments)


Joined: 08/09/2010
Groups: foldeRNA

Just to clarify, it's not a persistent problem; I got past it. I just thought it could potentially give a clue to a deeper issue.

infjamc's picture
User offline. Last seen 1 day 7 hours ago. Offline
Joined: 02/20/2009
Groups: Contenders

This problem was most likely a technical artifact-- namely, the result of the way that the puzzle was set up. Specifically, because the puzzle was designed in such a way that the backbone of the segments adjacent to the disembodied AA must match up almost perfectly or suffer from huge score penalty, the program might find that stretching atom-atom bonds to ridiculous lengths actually scored slightly better.

The easiest solution, then, would probably be undoing the move as you have done. Alternatively, rebuilding should also fix the problem...

Joined: 08/09/2010
Groups: foldeRNA

Yeah, I got around it just by wiggling one amino acid on the loop prior to doing a global wiggle. It seemed like it was a small "niche" to fit into to find that bug.

That makes sense though. Is this puzzle aimed at designing a loop that allows that arginine to penetrate the the other protein? - Perhaps to be followed by another design puzzle with a set loop segment number?

Joined: 12/27/2010
Groups: None

To duplicate this interesting effect, reset the puzzle, select the mutable loop and press wiggle.

Joined: 06/17/2010
Status: Open » Closed

Closing for now. Not reported any more.

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, Boehringer Ingelheim, RosettaCommons