puzzle picture
386: De-novo Freestyle
Status: Closed


Name: 386: De-novo Freestyle
Status: Closed
Created: 12/02/2010
Points: 100
Expired: 12/09/2010 - 23:00
Difficulty: Advanced
Description: It's been a while since we gave you a freestyle puzzle to work on, but this unsolved protein does not have any templates. We will post the secondary structure predictions in the puzzle comments when they come back from the SAM server.

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beta_helix's picture
User offline. Last seen 1 week 3 days ago. Offline
Joined: 05/09/2008
Groups: None
Please try to use these secondary structure predictions:

Here is the sequence logo predicted by the SAM server.

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the amino acid Leucine at residue 21 is highly predicted to be part of a helix. However, the Leucine at residue 29 is predicted to have an equal probability of being anything.

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
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