TNT?
| Case number: | 845799-988295 |
| Topic: | Biochem |
| Opened by: | spvincent |
| Status: | Closed |
| Type: | Question |
| Opened on: | Friday, August 20, 2010 - 04:24 |
| Last modified: | Sunday, June 5, 2011 - 12:43 |
Is the orange-coloured ligand really TNT? It looks like trinitro-something but not toluene.
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Fri, 08/20/2010 - 06:10
#2
Ah! Good question. So it's very similar molecule to TNT, but ours has a linker coming off of it with a biotin molecule attached (not shown in the puzzle) so that we can more easily test for binding. We figure that since we are designing the protein to primarily bind the nitro groups and the ring, that free TNT should also bind if we can design a binder for this TNT-Biotin molecule.
-Austin
Sun, 06/05/2011 - 12:43
#3
| Status: Open » Closed |
TNT puzzle gone, closing.
Austin will handle this one...