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GTPase Ras
Status: Closed

Summary

Name: GTPase Ras
Status: Closed
Created: 08/18/2010
Points: 100
Difficulty: Advanced
Description: The conformational change occurring in the small GTPase Ras is extremely important for the molecular basis of many cancers. The GTP-bound conformation of this protein should be in an ON state, signaling cell growth. Can you help it find this native fold?
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Comments

Joined: 05/19/2010
Groups: Cannabis Crew
How do we know it's in the On State?

Exactly what the subject says.

"The GTP-bound conformation of this protein should be in an ON state"

Is the shape that it's already in considered the On State?

jeff101's picture
User offline. Last seen 10 hours 41 min ago. Offline
Joined: 04/20/2012
Groups: Go Science
What is the highest score so far?

Below are two GTPase Ras contests that many have played,
along with their highest scores so far.
I think both contests use the same scoring system.
Can you score better?

http://fold.it/portal/node/992610 11727
http://fold.it/portal/node/988274 11708

jeff101's picture
User offline. Last seen 10 hours 41 min ago. Offline
Joined: 04/20/2012
Groups: Go Science
Another GTPase Ras puzzle has this hi score:
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