puzzle picture
296: Hold it! 3
Status: Closed


Name: 296: Hold it! 3
Status: Closed
Created: 05/02/2010
Points: 100
Expired: 05/05/2010 - 23:00
Difficulty: Intermediate
Description: Here's the next puzzle in the Hold it! series. This protein is binding a small molecule, and forming several hydrogen bonds at one end. This time things are already in a good position to form the hydrogen bonds, and they are held in place with constraints. We need you to mutate the residues around the small molecule to make better contacts! This puzzle will be relatively short!

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, Boehringer Ingelheim, RosettaCommons