Side chain reference scores in 254

Case number:699969-987294
Topic:General
Opened by:infjamc
Status:Closed
Type:Question
Opened on:Friday, January 29, 2010 - 00:40
Last modified:Tuesday, August 23, 2011 - 20:21

In the latest protein-DNA binding puzzle, mutating the alanines to cysteine does not incur the regular -17 penalty in the reference score, while the usage of large aromatics (Phe/Tyr/Trp and even His) now incur a 13/11/27/11-point penalty. Is this intentional to discourage their overuse relative to proteins found naturally?

(Fri, 01/29/2010 - 00:40  |  2 comments)


Joined: 09/18/2009
Groups: SETI.Germany

Wow, how do you know all of this?
Please tell me.

I also want a score spreadsheet.

Joined: 06/17/2010
Status: Open » Closed

Old puzzle. Closing case.

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