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226 (<150): Mini-CASP 10 - Freestyle
Status: Closed

Summary

Name: 226 (<150): Mini-CASP 10 - Freestyle
Status: Closed
Created: 11/25/2009
Points: 100
Expired: 12/02/2009 - 23:00
Difficulty: Advanced
Description: Our 10th Mini-CASP target is another de-novo (or ab-initio) target. This means that there is no solved structure that has a similar sequence that we can start our predictions from. This is exciting because template-free targets are rare (in CASP8 only 11 of the 128 targets were free-modeling targets) so we are lucky to be able to predict this. Since we have no idea where to even start, we are giving you an extended chain to see what you come up with. This might not be easy, so we will give you Rosetta@home predictions for this target as puzzles next week. Until then, good luck freestyle folding! The secondary structure prediction is posted in the puzzle comments. For players with fewer than 150 global points.
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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, Boehringer Ingelheim, RosettaCommons