puzzle picture
206: Mini-CASP 6-Freestyle
Status: Closed

Summary

Name: 206: Mini-CASP 6-Freestyle
Status: Closed
Created: 10/07/2009
Points: 100
Expired: 10/13/2009 - 23:00
Difficulty: Advanced
Description: Here is the next Mini-CASP target whose solved structure will be released soon. Again we are giving you an extended chain to see what you come up with. This might be very difficult, since this blind prediction has 121 residues, so we will give you Rosetta@home predictions for this target next week. Until then, good luck freestyle folding! We will post the secondary structure predictions for this puzzle in the puzzle comments.
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Comments

beta_helix's picture
User offline. Last seen 1 day 1 hour ago. Offline
Joined: 05/09/2008
Groups: None
secondary structure predictions will be here!

As soon as I get the sequence logo secondary structure predictions back from the SAM server
(http://compbio.soe.ucsc.edu/SAM_T08/faq.html)
I will post them here!

beta_helix's picture
User offline. Last seen 1 day 1 hour ago. Offline
Joined: 05/09/2008
Groups: None
Secondary structure prediction results:

Here is the sequence logo predicted by the SAM server.

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the amino acid Valine at residue 101 is highly predicted to be part of a sheet. However, the Alanine at residue 61 is predicted to have an equal probability of being anything.

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons