I just starting folding a week or so ago and I'm enjoying it quite a bit. As I gain experience and learn more about certain strategies and read about other people's strategies, I'm starting to become more and more confused about what this project is intended to do.
From what I've read the goal is to show that through human's puzzle solving skills and the desire to do so, we might be better suited to solving these protein folding problems than a computer(s). But, it seems as though most of the strategies involve random combinations of global and local pulls, shakes and wiggles. Random iterations is what computers do best, so why get a bunch of people to do very slowly what a computer could be programmed to do very quickly? I guarantee a PC could reorganize random sidechains followed by a global wiggle faster than I could. Being inexperienced, maybe the answer is that the best of the best folders don't use random strategies, they shake, wiggle and pull for well thought out reasons?
Just looking for some of your thoughts.