Disulfid bond tool

Case number:845813-986242
Topic:Game: Tools
Opened by:ChristianK
Opened on:Friday, June 5, 2009 - 08:48
Last modified:Monday, June 4, 2012 - 11:49

As disulfid bond form it native proteins usually when there are two Cysteins next to each other but don't really form automatically in fold.it, it would be great if there would be a tool that lets me select two Cysteins and that pushes them together the right way to form a bond.
Simple having a rubber band between them isn't enough and doesn't produce disulfid bonds.

(Fri, 06/05/2009 - 08:48  |  2 comments)

Joined: 05/19/2009
Groups: Go Science

I think both in Rosetta 13 and Rosetta 14 it's nearly impossible to create a bonding between the cysteines.
I'm confident that there are cysteine bonds in the real native protein as those two cysteine in every puzzle are near to each other.
Could someone with access to the native check?

spmm's picture
User offline. Last seen 8 weeks 2 days ago. Offline
Joined: 08/05/2010
Groups: Void Crushers
Status: Open » Closed

disulphide bonds now operational - closed


Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, Boehringer Ingelheim, RosettaCommons