Self-fulfilling prophecy = Fold.it player strategies take their current form only as a reaction to the tools given.
Could it be that what we are seeing as a player strategy is nothing more than a reaction to the tools that were provided?
If the tool set given by Fold.it was different, the game playing/protein folding strategies would be very different. So what do we hope to learn here? How important is it to develop a broader set of folding tools with many different strategies and techniques.
For example, the game only saves a top score. If you make a bad move (loose many points by stressing the backbone in various ways) as you struggle back, resolving the issues in neighboring pairs, you might make some very good, new folds. However, if the overall score is not a new high, any interim work is lost should you quit before reaching a new high. So.... the only worthwhile increase producing scores are the small incremental scores you might see by walking the backbone (wiggling two or three segments at a time ONLY). Likewise, any serious large scale rebuilding is totally impossible unless you are successful. Not many will be fortunate enough to achieve a new top score after a major rebuild of more than a segment or two at a time.
Imagine if there were many different folding tools? I could name a dozen.