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Joined: 05/18/2008
Groups: Rakata

I've not been able to figure out how to launch the "tweak" processes mentioned on July 2 - rotation and idealization. If anyone has information to share on this it would be much appreciated.

Diderot's picture
User offline. Last seen 1 year 18 weeks ago. Offline
Joined: 05/09/2008
1. Right click on a sheet

1. Right click on a sheet or a helix. The pie menu will open up.

2. Choose "tweak." The option "tweak" will not appear if the sheet or helix is currently unable to be tweaked based on the structures assigned to it and its neighbors. If this is the case, you will see "tweak help" instead. Do what "tweak help" tells you, then continue.

3. When tweak is active, you will see a purple dot and two purple curved arrows on both sides of your sheet or helix. The dot is the straighten function. The arrows will twist the element.


--Tweak will also adjust the loop amino acids on either end of the element you are tweaking. This is why it needs at least three of them. Sometimes this generates strange results; for example, when you have a single helix and a protein otherwise nothing but loops, the two arrows will just cause the protein to rotate, with no change in score. You'll need to lock at least one amino to see useful results here.

--Tweak usually decreases the score. Then local and global wiggles will do a lot to bring it back up again.

There's also a [[http://foldit.wikia.com/wiki/Tweak|tweak page at the wiki]], with some more information.

Joined: 05/18/2008
Groups: Rakata
Very powerful tool, thanks

Very powerful tool, thanks for sharing. What is meant by "selection" in the help comment?


Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, Boehringer Ingelheim, RosettaCommons