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Joined: 05/10/2008
Groups: None

So I have a general question about the tools underneath Foldit. When we find a max score using Foldit, how closely does would that that reflect the minimum energy state for a protein, and how closely would that reflect the native protein state?

I assume that there must be a lot of simplifications to even get this to function on a PC and I don't expect anything close to perfection from this amazing tool. I'd just like to get a better sense of where it is. Given that this is a competition, what are the chances the Foldit is accurate is enough to identify the native state?

Joined: 05/11/2008
Groups: CASP8 team
We're trying to figure out

We're trying to figure out that question ourselves. We're comparing the foldit results with actual results in an attempt to get an actual RMSD value of sorts


Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
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