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2120: Electron Density Reconstruction 6
Status: Closed
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Summary
| Name: | 2120: Electron Density Reconstruction 6 |
|---|---|
| Status: | Closed |
| Created: | 03/11/2022 |
| Points: | 100 |
| Expired: | 03/18/2022 - 23:00 |
| Difficulty: | Intermediate |
| Description: | The structure of this protein has already been solved and published, but close inspection suggests that there are some problems with the published solution. We'd like to see if Foldit players can use the same electron density data to reconstruct a better model. In addition to the protein chain, puzzle includes a glutathione ligand that is fixed in place.
Sequence:
AECSVDIQGNDQMQFNTNAITVDKSCKQFTVNLSHPGNLPKNVMGHSWVLSTAADMQGVVTDGMASGLDKDYLKPDDSRVIAHTKLIGSGEKDSVTFDVSKLKEGEQYMFFCTFPGHSALLKGTLTLK
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| Categories: | Electron Density, Overall, Prediction |
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We were told "puzzle includes a glutathione ligand that is fixed in place". I'm just not seeing it.
There don't seem to be any secondary structure type "M" segments. All the segments have normal amino acid codes, no type "x" segments.
I did just notice that the puzzle starts with a disulfide bridge.
I don't see anything that looks it could be a glutathione, but I guess I can keep looking.