Lab Report #27: Foldit gets a makeover

Foldit scientists from the University of Washington and Vanderbilt University discuss Foldit's new user interface.

NEWS
- A brand new user interface for Foldit puzzles

PUZZLE UPDATES
- Small molecule design for PROTAC drug development

DESIGN OF THE MONTH
- A small molecule design by an anonymous player from Puzzle 2062: VHL Ligand Design: Round 2, with an aromatic ring system backing up a key hydroxyl that makes critical H-bonds to the target. Take a look for yourself in the December Design of the Month sandbox puzzle.

(Wed, 12/01/2021 - 14:01  |  1 comment)
LociOiling's picture
User offline. Last seen 1 hour 4 min ago. Offline
Joined: 12/27/2012
Groups: Beta Folders
efflux

rmoretti mentions efflux in his review of the December 2021 Design of the Month.

Efflux in this context is the process of removing toxic materials from cells.

Walt Whitman's Song of Myself mentions efflux:

Partaker of influx and efflux I, extoller of hate and conciliation

Earlier in the poem, he makes the biochemistry aspect clear:

For every atom belonging to me as good belongs to you.

Less poetic version for the reference on the wiki:

https://foldit.fandom.com/wiki/Efflux

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, Boehringer Ingelheim, RosettaCommons