puzzle picture
Design of the Month: August 2021
Status: Closed

Summary

Name: Design of the Month: August 2021
Status: Closed
Created: 07/31/2021
Points: 0
Expired: 08/31/2021 - 23:00
Difficulty: Intermediate
Description: This sandbox puzzle features a designed binder for the TGF receptor, created by an anonymous player in Puzzle 2014. The hydrophobic residues at the interface will make for tight binding. The polar residues at the binding interface satisfy buried polar atoms on the target, but they also ensure that the binder will fold even in the absence of the target. For more, check out Foldit Lab Report #23 on YouTube! This sandbox puzzle is non-competitive and will not award any points.

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Top Groups

RankGroupScorePoints
1Go Science10,6440
2Marvin's bunch10,5830
3L'Alliance Francophone10,5630
4Contenders10,5490
5Gargleblasters10,5450

Top Evolvers

RankPlayerGroupScorePoints
1NinjaGreg 19 15 Go Science10,6440
2puxatudo 30 337 Go Science10,6360
3toshiue 1 32 Go Science10,5750

Top Soloists



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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, Boehringer Ingelheim, RosettaCommons