puzzle picture
Beginner Puzzle (<150): Docking Design
Status: Closed

Summary

Name: Beginner Puzzle (<150): Docking Design
Status: Closed
Created: 01/27/2014
Points: 100
Expired: 03/25/2021 - 23:00
Difficulty: Beginner
Description: We are giving you a helix positioned over a hydrophobic groove where binding occurs in nature. You can mutate any residue on the helix but none on the native binding region. Try to look for favorable hydrophobic interactions in this groove while maintaining the helix. For players with fewer than 150 global points.

START HERE:

If you are new to Foldit, here are detailed instructions to get you started:
http://fold.it/portal/node/988864
_____________________________

If you want to fold proteins, know that there are many ways to play and this variety is the main value of Foldit :
- try all puzzles not only "Beginners" ones,
- fold first the ones you like the most,
- try it by yourself to understand what works and what doesn't,
- ask for tips in global chat when you think you don't understand something.

Make sure you have followed these tutorials:
- Lonely Sheets,
- Lock and Lower,
- Rebuild,
- Structure and Rebuild,
- Movin' Along,
- Control over Clashing,
- Intro to Design,
- Swappin' Sidechains,
- Mass Mutate,
- Insertion and Deletion

before starting this puzzle.

Categories: Beginner

Top Groups

RankGroupScorePoints
1Czech National Team10,315100
2Go Science10,26976
3BIOL1107 with Jessica10,23756
4Coastal Biochemistry10,20841
5CHM 232 Lab GVSU10,09529

Top Soloists

RankPlayerGroupScorePoints
1Hillbillie 70 138  10,327100
2roarshock 70 252  10,31997
3vybi 70 73 Czech National Team10,31593
4kitsoune 70 110  10,30789
5simmsj3 70 1810  10,30386


Need this puzzle? Log in to download.  

Comments

No comments yet.
User login
Download links:
  Windows    OSX    Linux  
Windows
(7/8/10)
OSX
(10.12 or later)
Linux
(64-bit)

Are you new to Foldit? Click here.

Are you a student? Click here.

Are you an educator? Click here.
Social Media


Search
Only search fold.it
Other Games: Mozak
Recommend Foldit
Topics
Top New Users
Sitemap

Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons