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1921: Designable Linker: Coronavirus Spike Binder
Status: Closed
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Evolvers
1 | Dudit 51 112 | Go Science | 25,167 | 100 | 2 | toshiue 8 168 | Go Science | 25,163 | 98 | 3 | mirp 1 8 | Go Science | 25,163 | 95 | 4 | ZeroLeak7 18 4 | Go Science | 25,162 | 92 | 5 | Bruno Kestemont 2 7 | Go Science | 25,162 | 89 | 6 | ichwilldiesennamen 4 1 | Go Science | 25,152 | 87 | 7 | Dhalion 3 96 | Go Science | 25,145 | 84 | 8 | Czim 6 115 | Go Science | 25,145 | 82 | 9 | Keresto 37 435 | Gargleblasters | 25,138 | 79 | 10 | Joanna_H 48 77 | Gargleblasters | 25,128 | 77 | 11 | NinjaGreg 17 19 | Go Science | 25,125 | 75 | 12 | Mike Lewis 15 24 | Gargleblasters | 25,114 | 72 | 13 | Skippysk8s 25 28 | Gargleblasters | 25,112 | 70 | 14 | OWM3 20 20 | Gargleblasters | 25,051 | 68 | 15 | Bletchley Park 14 46 | Contenders | 25,025 | 66 | 16 | Galaxie 5 9 | Anthropic Dreams | 24,944 | 64 | 17 | Philzord 40 88 | Go Science | 24,941 | 62 | 18 | phi16 13 17 | Anthropic Dreams | 24,918 | 60 | 19 | alcor29 11 66 | Anthropic Dreams | 24,891 | 58 | 20 | silent gene 7 13 | Go Science | 24,881 | 56 | 21 | Ashrai 32 62 | Gargleblasters | 24,872 | 54 | 22 | alwen 42 202 | Anthropic Dreams | 24,870 | 53 | 23 | kyoota 10 79 | Go Science | 24,857 | 51 | 24 | robgee 12 16 | Anthropic Dreams | 24,754 | 49 | 25 | Blipperman 24 36 | Gargleblasters | 24,646 | 48 | Need this puzzle? Log in to download.
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Residue Count (max +550)
Penalizes extra residues inserted beyond the starting 240, at a cost of 55 points per residue. Players may use up to 250 residues in total.
Core Existence (max +2400)
Ensures that at least 35 percent of residues are buried in the core of the monomer unit.
Interaction Energy (max +500)
Monitors that all large PHE, TYR, and TRP residues are scoring well.
SS Design (max +500)
Prohibits CYS residues. Penalizes GLY, ALA residues in sheets. Penalizes GLY, ALA, SER, THR in helices.
Ideal Loops (max +500)
Penalizes any loop region that does not match one of the Building Blocks in the Blueprint tool. Use "Auto Structures" to see which regions of your protein count as loops.