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Case number:845799-2010478
Opened by:alcor29
Opened on:Thursday, October 1, 2020 - 17:59
Last modified:Saturday, October 3, 2020 - 18:59

I seem to be able to deal with SASA and SC well enough. Can't figure out however, how to improve DDG. Can you suggest what specifics determine the DDG score, or what are the alternative ways to improve it? Thanks.

(Thu, 10/01/2020 - 17:59  |  2 comments)

agcohn821's picture
User offline. Last seen 8 hours 23 min ago. Offline
Joined: 11/05/2019
Groups: Foldit Staff

Hi Alcor29

Thank you so much for your question--I have passed it along to the team.

bkoep's picture
User offline. Last seen 5 hours 36 min ago. Offline
Joined: 11/15/2012
Groups: Foldit Staff

DDG measures how much the binding interface contributes to your score. DDG should improve (become more negative) with tight packing around hydrophobic residues on the target, and H-bonds to polar atoms on the target.


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