LCB1 Coronavirus Spike Binder (corrected)
|Name:||LCB1 Coronavirus Spike Binder (corrected)|
|Expired:||09/30/2020 - 23:00|
|Description:||Note: This replaces the original LCB1 puzzle, which had some incorrect settings for Core Exists, Ideal Loops, and SS Design Objectives.
This is a non-competitive "sandbox" puzzle where you can explore a protein designed by IPD scientists. The starting structure is LCB1, a designed protein that binds to the coronavirus spike protein to block viral infection. This design was just one of millions of proteins designed by researchers. It was chosen for testing because it has excellent binder metrics. Lab tests have shown that this binder can potently inhibit viral infection in a test tube, but further tests are needed to determine safety and efficacy in animals.
Read more about this protein on the Foldit blog.
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