LCB1 Coronavirus Spike Binder
|Name:||LCB1 Coronavirus Spike Binder|
|Expired:||09/30/2020 - 23:00|
|Description:||Note: This puzzle had some incorrect settings for Core Exists, Ideal Loops, and SS Design Objectives. It has been replaced with an updated LCB1 puzzle.
This is a non-competitive "sandbox" puzzle where you can explore a protein designed by IPD scientists. The starting structure is LCB1, a designed protein that binds to the coronavirus spike protein to block viral infection. This design was just one of millions of proteins designed by researchers. It was chosen for testing because it has excellent binder metrics. Lab tests have shown that this binder can potently inhibit viral infection in a test tube, but further tests are needed to determine safety and efficacy in animals.
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