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1877: Coronavirus Anti-inflammatory Design: Round 10
Status: Closed
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Soloists
1 | ZeroLeak7 18 4 | Go Science | 11,894 | 100 | 2 | georg137 27 68 | Contenders | 11,877 | 98 | 3 | Joanna_H 48 77 | Gargleblasters | 11,860 | 95 | 4 | Galaxie 5 9 | Anthropic Dreams | 11,823 | 93 | 5 | Phyx 65 32 | Go Science | 11,772 | 90 | 6 | sgeldhof 87 57 | | 11,768 | 88 | 7 | Pazithi 55 97 | Gargleblasters | 11,765 | 86 | 8 | mirp 1 8 | Go Science | 11,757 | 83 | 9 | BootsMcGraw 16 10 | Contenders | 11,745 | 81 | 10 | NinjaGreg 17 19 | Go Science | 11,715 | 77 | 11 | Skippysk8s 25 28 | Gargleblasters | 11,714 | 75 | 12 | Sadaharu06.jp 87 2553 | | 11,712 | 73 | 13 | Bletchley Park 14 46 | Contenders | 11,668 | 71 | 14 | CharlieFortsCon... 41 67 | Contenders | 11,658 | 69 | 15 | stomjoh 87 87 | | 11,639 | 67 | 16 | nicobul 54 53 | L'Alliance Francophone | 11,635 | 65 | 17 | nspc 70 29 | Go Science | 11,623 | 63 | 18 | grogar7 53 2 | Anthropic Dreams | 11,607 | 61 | 19 | malphis 87 600 | | 11,584 | 60 | 20 | johnmitch 87 11 | | 11,570 | 58 | 21 | Ashrai 32 62 | Gargleblasters | 11,560 | 56 | 22 | phi16 13 17 | Anthropic Dreams | 11,557 | 55 | 23 | Bruno Kestemont 2 7 | Go Science | 11,520 | 53 | 24 | ucad 87 18 | | 11,519 | 52 | 25 | dcrwheeler 87 6 | | 11,510 | 50 | Need this puzzle? Log in to download.
Comments
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Buried Unsats (max +100)
Penalizes 60 points for each polar atom that cannot make any H-bonds. Note that the frozen target includes 15 buried unsats that may be impossible to satisfy.
Residue Count (max +275)
Penalizes extra residues inserted beyond the starting 151, at a cost of 55 points per residue. Players may use up to 156 residues in total.
Core Existence (max +1000)
Ensures that at least 25 percent of residues are buried in the core of the monomer unit.
Ideal Loops (max +500)
Penalizes any loop region that does not match one of the Building Blocks in the Blueprint tool. Use "Auto Structures" to see which regions of your protein count as loops.
SS Design (max +500)
Penalizes all CYS residues. Penalizes GLY, ALA residues in sheets. Penalizes GLY, ALA, SER, THR in helices.