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1877: Coronavirus Anti-inflammatory Design: Round 10
Status: Closed
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Evolvers
1 | Formula350 29 48 | Gargleblasters | 11,860 | 100 | 2 | Pazithi 55 97 | Gargleblasters | 11,856 | 98 | 3 | Skippysk8s 25 28 | Gargleblasters | 11,855 | 95 | 4 | OWM3 20 20 | Gargleblasters | 11,850 | 93 | 5 | HuubR 26 49 | Gargleblasters | 11,850 | 90 | 6 | Mike Lewis 15 24 | Gargleblasters | 11,845 | 88 | 7 | Galaxie 5 9 | Anthropic Dreams | 11,823 | 86 | 8 | Jpilkington 50 600 | Gargleblasters | 11,764 | 83 | 9 | Blipperman 24 36 | Gargleblasters | 11,736 | 81 | 10 | phi16 13 17 | Anthropic Dreams | 11,731 | 79 | 11 | alwen 42 202 | Anthropic Dreams | 11,728 | 77 | 12 | MrZanav 80 127 | Anthropic Dreams | 11,724 | 75 | 13 | Bletchley Park 14 46 | Contenders | 11,710 | 73 | 14 | Ashrai 32 62 | Gargleblasters | 11,701 | 71 | 15 | ichwilldiesennamen 4 1 | Go Science | 11,695 | 69 | 16 | mirp 1 8 | Go Science | 11,693 | 67 | 17 | silent gene 7 13 | Go Science | 11,679 | 65 | 18 | Dudit 51 112 | Go Science | 11,672 | 63 | 19 | Dhalion 3 96 | Go Science | 11,666 | 61 | 20 | Czim 6 115 | Go Science | 11,662 | 60 | 21 | zo3xiaJonWeinberg 80 141 | Go Science | 11,661 | 58 | 22 | georg137 27 68 | Contenders | 11,642 | 56 | 23 | CharlieFortsCon... 41 67 | Contenders | 11,641 | 55 | 24 | martinzblavy 59 72 | Contenders | 11,636 | 53 | 25 | nspc 70 29 | Go Science | 11,623 | 52 | Need this puzzle? Log in to download.
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Buried Unsats (max +100)
Penalizes 60 points for each polar atom that cannot make any H-bonds. Note that the frozen target includes 15 buried unsats that may be impossible to satisfy.
Residue Count (max +275)
Penalizes extra residues inserted beyond the starting 151, at a cost of 55 points per residue. Players may use up to 156 residues in total.
Core Existence (max +1000)
Ensures that at least 25 percent of residues are buried in the core of the monomer unit.
Ideal Loops (max +500)
Penalizes any loop region that does not match one of the Building Blocks in the Blueprint tool. Use "Auto Structures" to see which regions of your protein count as loops.
SS Design (max +500)
Penalizes all CYS residues. Penalizes GLY, ALA residues in sheets. Penalizes GLY, ALA, SER, THR in helices.