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1876: Symmetric Trimer Design: H-bond Networks
Status: Closed

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RankGroupScorePoints
1Contenders20,305100
2Go Science20,13971
3Anthropic Dreams19,83749
4Beta Folders19,38333
5L'Alliance Francophone19,04222
6Marvin's bunch18,55614
7Gargleblasters18,2408
8Void Crushers17,4225
9Russian team15,9753
10BOINC@Poland15,7312
11Hold My Beer15,2991
12Team Poland15,2121
13Team South Africa14,3721
14Team Canada10,7951
15Rechenkraft.net2,5011
16Macromolecules@MQ 202001


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bkoep's picture
User offline. Last seen 1 day 5 hours ago. Offline
Joined: 11/15/2012
Groups: Foldit Staff
Objectives

Buried Unsats (max +500)
Penalizes polar atoms that cannot make hydrogen bonds, -150 points per atom (not including symmetric copies).

Core Existence: Monomer (max +2000)
Ensures that at least 20 residues are buried in the core of the monomer unit.

Core: Complex (max +0)
Awards no bonuses or penalties. Click Show to see which residues count as "Core" for the H-bond Network objective.

H-bond Network (max +1800)
Rewards networks that comprise at least 3 H-bonds involving core residues.
Between 1 and 9 H-bonds should cross the interface between symmetric units.
Networks must be at least 75% satisfied (i.e. 75% of all bondable atoms in a network must make a H-bond).

SS Design (max +500)
Penalizes all CYS residues. Penalizes GLY, ALA residues in sheets. Penalizes GLY, ALA in helices.

Ideal Loops (max +500)
Penalizes any loop region that does not match one of the Building Blocks in the Blueprint tool. Use "Auto Structures" to see which regions of your protein count as loops.

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons