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1870: Symmetric Trimer Design: Limited Interface
Status: Closed
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Soloists
1 | ZeroLeak7 46 97 | Go Science | 20,499 | 100 | 2 | grogar7 46 19 | Anthropic Dreams | 20,270 | 97 | 3 | Phyx 46 109 | Go Science | 20,252 | 93 | 4 | Bruno Kestemont 3 2 | Go Science | 20,245 | 89 | 5 | spvincent 29 12 | Contenders | 20,163 | 86 | 6 | fiendish_ghoul 46 34 | | 20,075 | 83 | 7 | dcrwheeler 46 4 | | 19,911 | 79 | 8 | Mike Cassidy 46 60 | Void Crushers | 19,863 | 76 | 9 | sgeldhof 46 37 | | 19,858 | 73 | 10 | mirp 46 1458 | Go Science | 19,812 | 70 | 11 | Pazithi 46 62 | Gargleblasters | 19,771 | 68 | 12 | silent gene 24 66 | Go Science | 19,748 | 65 | 13 | LociOiling 2 1 | Beta Folders | 19,735 | 62 | 14 | Galaxie 1 3 | Anthropic Dreams | 19,720 | 60 | 15 | stomjoh 46 92 | | 19,692 | 57 | 16 | Mike Lewis 46 1458 | Gargleblasters | 19,646 | 55 | 17 | georg137 18 35 | Contenders | 19,639 | 52 | 18 | hpaege 46 1458 | | 19,582 | 48 | 19 | HuubR 30 58 | Gargleblasters | 19,530 | 46 | 20 | spdenne 46 338 | Void Crushers | 19,478 | 44 | 21 | g_b 46 24 | | 19,430 | 42 | 22 | MrZanav 20 82 | Anthropic Dreams | 19,425 | 40 | 23 | Joanna_H 46 1458 | Gargleblasters | 19,412 | 38 | 24 | BootsMcGraw 10 7 | Contenders | 19,405 | 37 | 25 | malphis 46 1458 | | 19,394 | 35 | Need this puzzle? Log in to download.
Comments
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Buried Unsats (max +500)
Penalizes polar atoms that cannot make hydrogen bonds, -150 points per atom (not including symmetric copies).
Core Existence: Monomer (max +2200)
Ensures that at least 22 residues are buried in the core of the monomer unit.
Core Limit: Complex (max +500)
Checks that no more than 87 residues are buried in the symmetric complex, including the interface between monomer units.
SS Design (max +500)
Penalizes all CYS residues. Penalizes GLY, ALA residues in sheets. Penalizes GLY, ALA, SER, THR in helices.
Ideal Loops (max +500)
Penalizes any loop region that does not match one of the Building Blocks in the Blueprint tool. Use "Auto Structures" to see which regions of your protein count as loops.