puzzle picture
1870: Symmetric Trimer Design: Limited Interface
Status: Closed

Groups

RankGroupScorePoints
1Go Science20,499100
2Contenders20,43673
3Anthropic Dreams20,27752
4Void Crushers19,86336
5Gargleblasters19,77124
6Beta Folders19,74016
7Marvin's bunch19,07610
8L'Alliance Francophone18,2216
9Australia17,4374
10Hold My Beer17,0432
11BOINC@Poland16,8581
12Russian team16,3101
13Team Canada11,9001
14Italiani Al Lavoro11,8921
15hhv901
16CHEM1210/1020 TTU01
17Foldit Staff01


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bkoep's picture
User offline. Last seen 10 hours 31 min ago. Offline
Joined: 11/15/2012
Groups: Foldit Staff
Objectives

Buried Unsats (max +500)
Penalizes polar atoms that cannot make hydrogen bonds, -150 points per atom (not including symmetric copies).

Core Existence: Monomer (max +2200)
Ensures that at least 22 residues are buried in the core of the monomer unit.

Core Limit: Complex (max +500)
Checks that no more than 87 residues are buried in the symmetric complex, including the interface between monomer units.

SS Design (max +500)
Penalizes all CYS residues. Penalizes GLY, ALA residues in sheets. Penalizes GLY, ALA, SER, THR in helices.

Ideal Loops (max +500)
Penalizes any loop region that does not match one of the Building Blocks in the Blueprint tool. Use "Auto Structures" to see which regions of your protein count as loops.

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, Boehringer Ingelheim, RosettaCommons