puzzle picture
1865: Coronavirus Anti-inflammatory Design: Round 8
Status: Closed

Groups

RankGroupScorePoints
1Go Science12,000100
2Anthropic Dreams11,74480
3Void Crushers11,69063
4L'Alliance Francophone11,65949
5Contenders11,65437
6Gargleblasters11,64528
7Beta Folders11,32221
8Marvin's bunch11,29715
9BOINC@Poland11,04511
10Hold My Beer10,8488
11Russian team10,2975
12Team China9,3424
13Team South Africa9,2282
14xkcd8,7792
15Italiani Al Lavoro8,6721
16Mojo Risin'8,2331
17Boilermakers7,0911
18Team Canada01
19Kotocycle01
20SETI.Germany01
21Kettering University FoldIt01
22DSN @ Home01
23Foldit Staff01


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bkoep's picture
User offline. Last seen 12 hours 55 min ago. Offline
Joined: 11/15/2012
Groups: Foldit Staff
Objectives

Buried Unsats (max +100)
Penalizes 60 points for each polar atom that cannot make any H-bonds. Note that the frozen target includes 15 buried unsats that may be impossible to satisfy.

Residue Count (max +275)
Penalizes extra residues inserted beyond the starting 151, at a cost of 55 points per residue. Players may use up to 156 residues in total.

Core Existence (max +1000)
Ensures that at least 25 percent of residues are buried in the core of the monomer unit.

Ideal Loops (max +500)
Penalizes any loop region that does not match one of the Building Blocks in the Blueprint tool. Use "Auto Structures" to see which regions of your protein count as loops.

SS Design (max +500)
Penalizes all CYS residues. Penalizes GLY, ALA residues in sheets. Penalizes GLY, ALA in helices.

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons