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1853: Symmetric Trimer Design: Buried Unsats
Status: Closed
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Soloists
51 | Vinara 75 81 | | 19,859 | 16 | 52 | Anfinsen_slept_here 16 41 | Go Science | 19,628 | 15 | 53 | Nicm25 75 1437 | | 19,551 | 14 | 54 | Czim 75 1437 | Go Science | 19,492 | 14 | 55 | Hellcat6 59 93 | Go Science | 19,476 | 13 | 56 | cbwest 75 727 | | 19,428 | 13 | 57 | Tehnologik1 75 645 | Anthropic Dreams | 19,248 | 12 | 58 | jobo0502 75 22 | L'Alliance Francophone | 19,228 | 12 | 59 | jausmh 20 24 | Marvin's bunch | 19,096 | 11 | 60 | Merf 75 86 | | 19,079 | 11 | 61 | alwen 44 1437 | Anthropic Dreams | 19,061 | 10 | 62 | WBarme1234 75 23 | | 18,904 | 10 | 63 | OWM3 75 1437 | Gargleblasters | 18,817 | 9 | 64 | johnmitch 75 1437 | | 18,706 | 9 | 65 | Sadaharu06.jp 75 1437 | | 18,701 | 8 | 66 | CAN1958 75 1040 | | 18,635 | 8 | 67 | alcor29 5 7 | Anthropic Dreams | 18,626 | 8 | 68 | GuR0 75 1437 | | 18,610 | 7 | 69 | Mikisp 75 1437 | | 18,502 | 7 | 70 | Todd6485577 75 1437 | Hold My Beer | 18,466 | 7 | 71 | jawz101 75 1040 | | 18,401 | 6 | 72 | HuubR 34 88 | Gargleblasters | 18,182 | 6 | 73 | momadoc 75 1437 | | 18,115 | 6 | 74 | AlkiP0Ps 75 50 | | 17,974 | 5 | 75 | sitlux 75 1437 | | 17,969 | 5 | Need this puzzle? Log in to download.
Comments
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Buried Unsats (max +300)
Penalizes polar atoms that cannot make hydrogen bonds, -30 points per atom (not including symmetric copies).
Core Existence: Monomer (max +3000)
Ensures that at least 30 residues are buried in the core of the monomer unit.
Core: Complex (max +0)
Awards no bonuses or penalties. Click Show to see which residues count as "Core" for the H-bond Network objective.
H-bond Network (max +1800)
Rewards networks that comprise at least two H-bonds involving core residues.
Between 1 and 9 H-bonds should cross the interface between symmetric units.
Networks must be at least 75% satisfied (i.e. 75% of all bondable atoms in a network must make a H-bond).
SS Design (max +500)
Penalizes all CYS residues. Penalizes GLY, ALA residues in sheets. Penalizes GLY, ALA in helices.
Ideal Loops (max +500)
Penalizes any loop region that does not match one of the Building Blocks in the Blueprint tool. Use "Auto Structures" to see which regions of your protein count as loops.