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1853: Symmetric Trimer Design: Buried Unsats
Status: Closed
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Evolvers
1 | Bletchley Park 8 8 | Contenders | 23,240 | 100 | 2 | Dhalion 46 1458 | Go Science | 23,220 | 97 | 3 | Czim 46 1458 | Go Science | 23,218 | 95 | 4 | toshiue 46 863 | Go Science | 23,213 | 92 | 5 | mirp 46 1458 | Go Science | 23,209 | 89 | 6 | pente_player 46 1458 | Go Science | 23,206 | 86 | 7 | Bruno Kestemont 3 2 | Go Science | 23,203 | 83 | 8 | ichwilldiesennamen 22 10 | Go Science | 23,189 | 81 | 9 | Galaxie 1 3 | Anthropic Dreams | 23,070 | 78 | 10 | lynnai 46 1458 | Anthropic Dreams | 23,012 | 76 | 11 | silent gene 24 66 | Go Science | 23,003 | 71 | 12 | Pazithi 46 62 | Gargleblasters | 22,833 | 69 | 13 | LastAndroid 46 1458 | Gargleblasters | 22,820 | 66 | 14 | Mike Lewis 46 1458 | Gargleblasters | 22,815 | 64 | 15 | Skippysk8s 34 28 | Gargleblasters | 22,793 | 62 | 16 | alwen 46 1458 | Anthropic Dreams | 22,758 | 60 | 17 | Pikamander2 39 863 | Go Science | 22,744 | 58 | 18 | MrZanav 20 82 | Anthropic Dreams | 22,629 | 56 | 19 | georg137 18 35 | Contenders | 22,553 | 54 | 20 | spdenne 46 338 | Void Crushers | 22,512 | 52 | 21 | Jpilkington 46 1458 | Gargleblasters | 22,395 | 51 | 22 | Dolichwier 46 1458 | Void Crushers | 22,381 | 49 | 23 | Blipperman 26 33 | Gargleblasters | 22,370 | 47 | 24 | OWM3 46 1458 | Gargleblasters | 22,275 | 46 | 25 | HuubR 30 58 | Gargleblasters | 22,159 | 44 | Need this puzzle? Log in to download.
Comments
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Buried Unsats (max +300)
Penalizes polar atoms that cannot make hydrogen bonds, -30 points per atom (not including symmetric copies).
Core Existence: Monomer (max +3000)
Ensures that at least 30 residues are buried in the core of the monomer unit.
Core: Complex (max +0)
Awards no bonuses or penalties. Click Show to see which residues count as "Core" for the H-bond Network objective.
H-bond Network (max +1800)
Rewards networks that comprise at least two H-bonds involving core residues.
Between 1 and 9 H-bonds should cross the interface between symmetric units.
Networks must be at least 75% satisfied (i.e. 75% of all bondable atoms in a network must make a H-bond).
SS Design (max +500)
Penalizes all CYS residues. Penalizes GLY, ALA residues in sheets. Penalizes GLY, ALA in helices.
Ideal Loops (max +500)
Penalizes any loop region that does not match one of the Building Blocks in the Blueprint tool. Use "Auto Structures" to see which regions of your protein count as loops.