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1853: Symmetric Trimer Design: Buried Unsats
Status: Closed
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Evolvers
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| 1 | Bletchley Park 11 36 | Contenders | 23,240 | 100 | | 2 | Dhalion 17 147 | Go Science | 23,220 | 97 | | 3 | Czim 19 195 | Go Science | 23,218 | 95 | | 4 | toshiue 2 86 | Go Science | 23,213 | 92 | | 5 | mirp 1 5 | Go Science | 23,209 | 89 | | 6 | pente_player 83 2324 | Go Science | 23,206 | 86 | | 7 | Bruno Kestemont 3 1 | Go Science | 23,203 | 83 | | 8 | ichwilldiesennamen 10 6 | Go Science | 23,189 | 81 | | 9 | Galaxie 4 4 | Anthropic Dreams | 23,070 | 78 | | 10 | lynnai 83 2324 | Anthropic Dreams | 23,012 | 76 | | 11 | silent gene 5 9 | Go Science | 23,003 | 71 | | 12 | Pazithi 40 44 | Gargleblasters | 22,833 | 69 | | 13 | LastAndroid 83 2324 | Gargleblasters | 22,820 | 66 | | 14 | Mike Lewis 49 75 | Gargleblasters | 22,815 | 64 | | 15 | Skippysk8s 23 34 | Gargleblasters | 22,793 | 62 | | 16 | alwen 67 720 | Anthropic Dreams | 22,758 | 60 | | 17 | Pikamander2 83 2324 | Go Science | 22,744 | 58 | | 18 | MrZanav 83 1053 | Anthropic Dreams | 22,629 | 56 | | 19 | georg137 15 38 | Contenders | 22,553 | 54 | | 20 | spdenne 77 46 | Void Crushers | 22,512 | 52 | | 21 | Jpilkington 34 333 | Gargleblasters | 22,395 | 51 | | 22 | Dolichwier 83 2324 | Void Crushers | 22,381 | 49 | | 23 | Blipperman 24 48 | Gargleblasters | 22,370 | 47 | | 24 | OWM3 32 14 | Gargleblasters | 22,275 | 46 | | 25 | HuubR 25 21 | Gargleblasters | 22,159 | 44 | Need this puzzle? Log in to download.
Comments
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Buried Unsats (max +300)
Penalizes polar atoms that cannot make hydrogen bonds, -30 points per atom (not including symmetric copies).
Core Existence: Monomer (max +3000)
Ensures that at least 30 residues are buried in the core of the monomer unit.
Core: Complex (max +0)
Awards no bonuses or penalties. Click Show to see which residues count as "Core" for the H-bond Network objective.
H-bond Network (max +1800)
Rewards networks that comprise at least two H-bonds involving core residues.
Between 1 and 9 H-bonds should cross the interface between symmetric units.
Networks must be at least 75% satisfied (i.e. 75% of all bondable atoms in a network must make a H-bond).
SS Design (max +500)
Penalizes all CYS residues. Penalizes GLY, ALA residues in sheets. Penalizes GLY, ALA in helices.
Ideal Loops (max +500)
Penalizes any loop region that does not match one of the Building Blocks in the Blueprint tool. Use "Auto Structures" to see which regions of your protein count as loops.