Foldit Lab Report #8: Check the Fridge

The COVID-19 lockdown continues -- but we have new updates and new puzzles anyway. Watch our latest lab report for more!

NEWS:
• Coronavirus binder testing has been delayed (0:25)

PUZZLE UPDATES:
• Aflatoxin enzymes need re-looping (1:01)
• Coronavirus protein prediction -- can you fold them all? (1:56)
• Coronavirus spike binders -- optimize 'em (2:45)
• Can protein design create a COVID-19 treatment? (3:32)
-- Controlling the cytokine storm: https://youtu.be/S63mysyN910

LAB UPDATES:
• Always check the fridge, because it might contain CRYSTALS (3:57)

DESIGN OF THE MONTH:
• Player Bruno Kestemont created a promising anti-inflamatory protein (5:06)

(Fri, 05/01/2020 - 14:30  |  8 comments)
Joined: 03/30/2013
Groups: Go Science
Surprise crystals

I love surprise crystals. Is that the real diffraction in the video? It looks like it diffracts to very nice resolution. What are the plans for publishing and depositing the structure.

bkoep's picture
User offline. Last seen 10 hours 30 min ago. Offline
Joined: 11/15/2012
Groups: None
6WI5

No, unfortunately that is not the diffraction for this protein (sorry!). That footage comes from an educational video by The Royal Institution: https://youtu.be/gLsC4wlrR2A

In fact, our test tube crystals did not diffract that well, but we were able to optimize the conditions and get diffraction to 1.83 Å.

The structure has already been deposited in the PDB here!

stomjoh's picture
User offline. Last seen 2 days 14 hours ago. Offline
Joined: 11/18/2012
Groups: None
Congrats!

WTG fiendish_ghoul and Bruno!

Joined: 04/25/2020
Groups: Go Science
design sharing

How do you share/submit a design you believe is viable?

Joined: 05/09/2008
Groups: None
Here you go!
Joined: 11/05/2019
Groups: None
Question

Hi SurferSleuth--I have passed your question on to the team! Thank you!

Joined: 03/19/2020
Groups: None
So no tests of protein design of fold.it ?

Man its really sux, that you unable to test all those protein designs,fold.it when you thing to release new statement about testing fold.it stuff ?

Joined: 05/26/2020
Groups: None
How to Activate Roku using Roku.com/link?

Roku.com/link, this is the page to activate and link your gadget. Select your device and if Roku is your choice, set the Language and Display. Establish a secure and active Internet. If this step is done, sign in to the Roku account to collect the code. Enter the code navigating to the page, Roku.com/link. Roku device activation is complete. If you are expecting more guidance, do not delay contacting the customer support techies.

Download links:
  Windows    OSX    Linux  
Windows
(7/8/10)
OSX
(10.12 or later)
Linux
(64-bit)

Are you new to Foldit? Click here.

Are you a student? Click here.

Are you an educator? Click here.
Other Games: Mozak
Search
Only search fold.it
Recommend Foldit
User login
Topics
Top New Users
Sitemap

Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons