puzzle picture
1818: Coronavirus Binder Design: Round 5
Status: Closed

Groups

RankGroupScorePoints
1Contenders16,420100
2Go Science16,39088
3Anthropic Dreams16,37477
4Gargleblasters16,36167
5Hold My Beer16,33758
6Marvin's bunch16,33050
7Beta Folders16,31143
8Void Crushers16,28337
9Russian team16,22131
10L'Alliance Francophone16,21826
11foldeRNA16,21322
12FoldIt@Netherlands16,16519
13Hun-Magyar Csapat16,16015
14Penny-Arcade16,14813
15BOINC@Poland16,14311
16CHNO Junkies16,1319
17Herobrine's Army16,1307
18SETI.Germany16,1306
19Wabash College Biochemistry16,1305
20GUGITBIOTECH16,1284
21Eastern Prehistoric Force16,1283
22Minions of TWIS16,1282
23Coastal Biochemistry16,1282
24Mojo Risin'16,1281
25Rechenkraft.net16,1271


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Comments

bkoep's picture
User is online Online
Joined: 11/15/2012
Groups: Foldit Staff
Objectives

Residue Count (max +550)
Penalizes extra residues inserted beyond the starting 192, at a cost of 55 points per residue. Players may use up to 202 residues in total.

Interaction Energy (max +500)
Monitors that all PHE, TYR, and TRP residues are scoring well.

Core Existence (max +2400)
Ensures that at least 28 percent of residues are buried in the core of the monomer unit.

Ideal Loops (max +500)
Penalizes any loop region that does not match one of the Building Blocks in the Blueprint tool. Use "Auto Structures" to see which regions of your protein count as loops.

SS Design (max +500)
Penalizes all CYS residues. Penalizes GLY, ALA residues in sheets. Penalizes GLY, ALA in helices.

Joined: 09/24/2012
Groups: Go Science
do you expect

that we try to keep the structure of the face binding to the virus ? (then bot mutating the binding without burials of the helices). ?

bkoep's picture
User is online Online
Joined: 11/15/2012
Groups: Foldit Staff
Up to you!

We think the starting interface looks pretty good, so it might be okay to keep the binding face the same and focus on refolding the sheets.

However, if you think you can improve the binding interface, go for it!

Joined: 03/30/2020
Groups: None
hüpfen

ich finde es ist nicht nur ein Spiel es hilft auch den Wissenschaftlern,rinenn das corona Virus zu bremsen.

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