Here's part 1, which may be helpful if you just finished the intro puzzles:;
It talks about some additional settings, and looks at the two pieces of protein that we've seen in the CoV puzzles so far.
Here's part 3, the final installment in this series. It shows moving the three-helix bundle to different spots, and has some tips for checking on how well you're doing in terms of hydrogen bonds.
It also takes a look at Puzzle 1811: Coronavirus Binder Design: Round 3, which has a few new wrinkles.
Hello,
Now I must eliminate the last virion at K154 (I experiment different mutation with design mode).
When I find, you are my results.
Regards,
See you,
Adrien T.
Biochemist (last years : familial hepls for my mother : now I help all my colleagues of the world against Cov).
PS : Good Luck !
Here's the video from Susume's recent livestream:
Here's part 2, showing how to make a bundle of helixes (or "helices" for you purists) that scores well:
https://youtu.be/H6w870nmNqw