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LociOiling's picture
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Groups: Beta Folders

Here's part 1, which may be helpful if you just finished the intro puzzles:;

https://youtu.be/w4WRNIqhpsw

It talks about some additional settings, and looks at the two pieces of protein that we've seen in the CoV puzzles so far.

LociOiling's picture
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CoV video, part 2

Here's part 2, showing how to make a bundle of helixes (or "helices" for you purists) that scores well:

https://youtu.be/H6w870nmNqw

LociOiling's picture
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CoV video, part 3

Here's part 3, the final installment in this series. It shows moving the three-helix bundle to different spots, and has some tips for checking on how well you're doing in terms of hydrogen bonds.

It also takes a look at Puzzle 1811: Coronavirus Binder Design: Round 3, which has a few new wrinkles.

https://youtu.be/-f5soD7iVOo

Joined: 12/09/2019
Groups: Go Science
Thanks dear colleague !

Hello,

Now I must eliminate the last virion at K154 (I experiment different mutation with design mode).

When I find, you are my results.

Regards,

See you,

Adrien T.
Biochemist (last years : familial hepls for my mother : now I help all my colleagues of the world against Cov).

PS : Good Luck !

LociOiling's picture
User offline. Last seen 11 hours 46 min ago. Offline
Joined: 12/27/2012
Groups: Beta Folders
and one from Susume

Here's the video from Susume's recent livestream:

https://www.youtube.com/watch?v=CzSCkJ0w4Dk

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